[Profacgen] Recombinant Rat Il23r Protein(Fc tag) (RH0268IL)
Cat.No.
RH0268IL
Synonyms
IL23R; interleukin 23 receptor
Species
Rat
Accession
Source
HEK293
Tag
Fc
Predicted N Terminal
Met
Form
Lyophilized from sterile PBS, pH 7.4, 5 % trehalose and 5 % mannitol.
Bio-activity
Measured by its ability to bind recombinant mouse IL12Bh (m)+mIL23Ah in a functional ELISA.
Molecular Mass
Recombinant Rat IL23R/Fc is a disulfide-linked homodimer. The reduced monomer comprises 608 amino acids and has a predicted molecular mass of 69.4 kDa.
Endotoxin
< 1.0 EU per 1 microgram of protein (determined by LAL method).
Purity
(75.1+16.6) by SDS-PAGE.
Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The functional IL-23 receptor complex consists of two receptor subunits, the IL-12 receptor beta 1 subunit (IL-12 R beta 1) and the IL-23-specific receptor subunit (IL-23 R).
