[Cytologics] CD4+/CD25+ Regulatory T Cells

[Cytologics]  CD4+/CD25+ Regulatory T Cells

SKU: 1308.

CD4+/CD25+ regulatory T cells (Tregs) are a subpopulation of T cells that play an important role in maintaining self-tolerance in the adaptive immune system by suppressing potentially deleterious activities of CD4+ helper T cells, which, if not regulated, can cause a variety of autoimmune disorders.

Human Peripheral Blood CD4+/CD25+ Tregs are enriched in a multi-step process by means of both positive and negative selection. Our Tregs are collected at FDA-licensed donor centers and further processed at our cell isolation laboratory.

CD4+/CD25+ Regulatory T Cells

This product consists of highly pure CD4+/CD25+ regulatory T-cells that express the intracellular transcription factor Foxp3. The CD4+ CD25- cell fraction can be used as effector cells in downstream inhibitory assays. You can expect >95% purity (CD4+ CD25+ expression) and >80% Foxp3 expression.

Each product is characterized by flow cytometry to ensure a highly pure and viable cell population. All donors are tested for HIV, Hepatitis B and C, WNV, CMV, and other blood-borne pathogens.

Biospecimens are obtained from properly consented donors. We conform to HIPAA standards to protect the privacy of the donor’s personal health information.

Human Material Precaution 
It is best to use caution when handling any human cells. We recommend all human cells should be handled as if potentially infectious following biosafety level 2 procedures.