[MuseChem] Degarelix acetate - CAS 934246-14-7 (acetate)

[MuseChem] Degarelix acetate - CAS 934246-14-7 (acetate)

Catalog Number: I006423

CAS Number: 934246-14-7 (acetate)

Molecular Formula: C84H107ClN18O18

Molecular Weight:1692.31

Purity: ≥95%

 

* For research use only. Not for human or veterinary use.

 

FE200486; FE-200486; FE 200486; ASP3550; ASP-3550; ASP 3550. tradename Firmagon.

 

C84H107ClN18O18

1692.31

Soluble in DMSO, not in water

≥95%

0 - 4°C for short term or -20 °C for long term

InChI=1S/C82H103ClN18O16.C2H4O2/c1-45(2)35-60(72(107)92-59(16-9-10-33-87-46(3)4)80(115)101-34-12-17-68(101)79(114)88-47(5)70(84)105)93-74(109)63(38-51-23-30-58(31-24-51)91-81(85)116)95-76(111)64(39-50-21-28-57(29-22-50)90-71(106)66-42-69(104)100-82(117)99

AUTFSFUMNFDPLH-KYMMNHPFSA-N

O=C([C@H](CC(N1)=O)NC1=O)NC2=CC=C(C[C@@H](C(N[C@H](CC3=CC=C(NC(N)=O)C=C3)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCNC(C)C)C(N4[C@H](C(N[C@H](C)C(N)=O)=O)CCC4)=O)=O)=O)=O)NC([C@H](CO)NC([C@@H](CC5=CC=CN=C5)NC([C@@H](CC6=CC=C(Cl)C=C6)NC([C@@H](CC7=CC=C8C=CC=CC8=C7)NC(

Degarelix, also known as FE-200486 and ASP-3550, is a long-acting, synthetic peptide with gonadotrophin-releasing hormone (GnRH) antagonistic properties. Degarelix targets and blocks GnRH receptors located on the surfaces of gonadotroph cells in the anterior pituitary, thereby reducing secretion of luteinizing hormone (LH) by pituitary gonadotroph cells and so decreasing testosterone production by interstitial (Leydig) cells in the testes. Degarelix acetate was approved in 2008.